Last updated: August 2026
This page provides general safety information about GLP-1 receptor agonist medications. It is not a substitute for the medical advice of your prescribing clinician. Read this page in full before beginning treatment, and discuss any questions with your provider.
If you are experiencing a medical emergency, call 911 immediately.
Compounded medications are not FDA-approved. The FDA does not review compounded drug products for safety, effectiveness, or quality.
Medications made available through 10/10Rx are compounded and dispensed by licensed pharmacies. 10/10Rx does not compound medications. Medical services are provided by independent, U.S.-licensed healthcare providers. Prescriptions are issued only when a licensed clinician determines that treatment is clinically appropriate following an evaluation.
The safety information on this page describes risks associated with the GLP-1 receptor agonist class of medications generally. Your prescribing clinician can discuss how this information applies to your individual treatment, medical history, and any other medications you take.
In studies in rodents, GLP-1 receptor agonists caused dose-dependent and treatment-duration-dependent thyroid C-cell tumors, including medullary thyroid carcinoma (MTC). It is not known whether these medications cause thyroid C-cell tumors, including MTC, in humans.
Do not use a GLP-1 receptor agonist if you or any of your family members have ever had medullary thyroid carcinoma (MTC), or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
Tell your provider right away if you develop:
Stop use and contact your provider immediately if you experience severe abdominal pain that will not go away, with or without vomiting. Pain may radiate from the abdomen to the back.
Gallbladder disease, including gallstones, has been reported. Tell your provider if you experience pain in the upper right abdomen, fever, yellowing of the skin or eyes, or clay-colored stools.
Risk is higher if you also take insulin or a sulfonylurea. Symptoms may include dizziness, blurred vision, anxiety, mood changes, sweating, slurred speech, hunger, confusion, shakiness, or rapid heartbeat. Tell your provider about every medication you take.
Nausea, vomiting, and diarrhea can cause dehydration, which may worsen kidney function or cause acute kidney injury. Maintain fluid intake and contact your provider if you cannot keep fluids down.
Seek emergency medical care for swelling of the face, lips, tongue, or throat; difficulty breathing or swallowing; severe rash or itching; fainting or dizziness; or very rapid heartbeat.
Tell your provider about any changes in vision during treatment, particularly if you have type 2 diabetes or a history of diabetic retinopathy.
Contact your provider immediately if you experience new or worsening depression, mood changes, or thoughts of self-harm. If you are in crisis, call or text 988 to reach the Suicide & Crisis Lifeline.
These medications slow the movement of food through the stomach. This can affect how other oral medications are absorbed, and it may increase the risk of aspiration during surgery or procedures requiring anesthesia or deep sedation. Tell every provider treating you — including surgeons, anesthesiologists, and dentists — that you are taking a GLP-1 medication.
Severe or persistent nausea, vomiting, diarrhea, or constipation may occur. Contact your provider if symptoms are severe, will not resolve, or prevent you from eating or drinking normally.
The most commonly reported side effects include:
This is not a complete list of possible side effects. Talk to your provider about any side effect that concerns you or does not go away.
Do not use these medications if you are pregnant, trying to become pregnant, or breastfeeding. Tell your provider immediately if you become pregnant during treatment. Discuss birth control options with your provider before starting treatment.
Before starting treatment, tell your provider about all medications, vitamins, and supplements you take, and about your full medical history — particularly any history of:
Because these medications slow stomach emptying, they may change how other oral medications are absorbed. This is particularly important for oral contraceptives and medications with a narrow therapeutic range.
Individual results vary and are not guaranteed. Weight management outcomes depend on many factors, including adherence, nutrition, physical activity, and individual medical circumstances. Treatment is intended to be used alongside lifestyle changes as directed by your provider.
Contact your 10/10Rx care team through your secure patient portal, or your prescribing clinician, to report any side effect.
You may also report adverse events directly to the FDA:
For suspected overdose or poisoning, contact Poison Control at 1-800-222-1222.
Prescription medications are non-refundable once dispensed. Services are available only in select states. Price varies by product and plan selected.
Questions about your treatment should be directed to your prescribing clinician through your secure patient portal.
10/10Rx
30423 Canwood Street, Agoura Hills, CA 91301
Tel: 844-326-5816 | Questions: 832-346-6080
Email: support@1010rx.com
Last updated: August 2026